Systematic Cellular Disease Models Reveal Synergistic Interaction of Trisomy 21 and GATA1 Mutations in Hematopoietic Abnormalities

Author:

Banno Kimihiko,Omori Sayaka,Hirata Katsuya,Nawa Nobutoshi,Nakagawa Natsuki,Nishimura Ken,Ohtaka Manami,Nakanishi Mahito,Sakuma Tetsushi,Yamamoto Takashi,Toki Tsutomu,Ito Etsuro,Yamamoto Toshiyuki,Kokubu Chikara,Takeda Junji,Taniguchi Hidetoshi,Arahori Hitomi,Wada Kazuko,Kitabatake Yasuji,Ozono Keiichi

Funder

Japan Science and Technology Agency

Ministry of Education, Culture, Sports, Science and Technology, Japan

JSPS

Japan Agency for Medical Research and Development (AMED)

Japan Foundation for Pediatric Research

Takeda Science Foundation

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference38 articles.

1. Changes in megakaryocytes in cases of thrombocytopenia: bone marrow aspiration and biopsy analysis;Bhasin;J. Clin. Diagn. Res.,2013

2. Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus;Byrska-Bishop;J. Clin. Invest.,2015

3. Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter;Chen;Nature,2009

4. Hematopoietic disorders in Down syndrome;Choi;Int. J. Clin. Exp. Pathol.,2008

5. Identification of the hemogenic endothelial progenitor and its direct precursor in human pluripotent stem cell differentiation cultures;Choi;Cell Rep.,2012

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