DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks

Author:

Saha Sourav,Sun Yilun,Huang Shar-yin Naomi,Baechler Simone Andrea,Pongor Lorinc Sandor,Agama Keli,Jo Ukhyun,Zhang Hongliang,Tse-Dinh Yuk-Ching,Pommier Yves

Funder

Center for Cancer Research, the Intramural Program of the National Cancer Institute

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference71 articles.

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2. Topoisomerase 3β is the major topoisomerase for mRNAs and linked to neurodevelopment and mental dysfunction;Ahmad;Nucleic Acids Res.,2017

3. Type IA topoisomerases can be “magicians” for both DNA and RNA in all domains of life;Ahmad;RNA Biol.,2017

4. Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets;Bedford;Nat. Rev. Drug Discov.,2011

5. SF3B1-targeted Splicing Inhibition Triggers Global Alterations in Transcriptional Dynamics and R-Loop Metabolism;Castillo-Guzman;bioRxiv,2020

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