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Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate

  • Published:2021-01 Issue:1 Volume:34 Page:108588
  • ISSN:2211-1247
  • Container-title:Cell Reports
  • language:en
  • Short-container-title:Cell Reports

Author:

Hughes Robert O.,Bosanac Todd,Mao Xianrong,Engber Thomas M.,DiAntonio Aaron,Milbrandt Jeffrey,Devraj Rajesh,Krauss Raul

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference42 articles.

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3. Mechanisms of axonal spheroid formation in central nervous system Wallerian degeneration;Beirowski;J. Neuropathol. Exp. Neurol.,2010

4. NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus;Cantó;Cell Metab.,2015

5. The ‘dying back’ process. A common denominator in many naturally occurring and toxic neuropathies;Cavanagh;Arch. Pathol. Lab. Med.,1979
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