Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q

Author:

Neggers Jasper E.ORCID,Paolella Brenton R.,Asfaw Adhana,Rothberg Michael V.,Skipper Thomas A.,Yang Annan,Kalekar Radha L.,Krill-Burger John M.,Dharia Neekesh V.,Kugener Guillaume,Kalfon Jérémie,Yuan Chen,Dumont Nancy,Gonzalez Alfredo,Abdusamad Mai,Li Yvonne Y.,Spurr Liam F.,Wu Westley W.,Durbin Adam D.,Wolpin Brian M.,Piccioni Federica,Root David E.,Boehm Jesse S.,Cherniack Andrew D.,Tsherniak Aviad,Hong Andrew L.,Hahn William C.,Stegmaier Kimberly,Golub Todd R.,Vazquez Francisca,Aguirre Andrew J.ORCID

Funder

Pancreatic Cancer Action Network

National Cancer Institute

Lustgarten Foundation

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference80 articles.

1. When membranes need an ESCRT: endosomal sorting and membrane remodelling in health and disease;Alfred;Swiss Med. Wkly.,2016

2. Critical role of ESCRT machinery in EGFR recycling;Baldys;Biochemistry,2009

3. The landscape of somatic copy-number alteration across human cancers;Beroukhim;Nature,2010

4. E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain;Berx;Oncogene,1996

5. ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking;Bishop;Mol. Biol. Cell,2000

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