Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome-Reference-Cited by-同舟云学术

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Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

Published:2018-11 Issue:6 Volume:25 Page:1525-1536.e7
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Platnich Jaye M.,Chung Hyunjae,Lau Arthur,Sandall Christina F.,Bondzi-Simpson Adom,Chen Huey-Miin,Komada Takanori,Trotman-Grant Aaron C.,Brandelli Jeremy R.,Chun Justin,Beck Paul L.,Philpott Dana J.,Girardin Stephen E.,Ho May,Johnson Roger P.,MacDonald Justin A.,Armstrong Glen D.,Muruve Daniel A.

Funder

Canadian Institutes of Health Research

Kidney Foundation of Canada

CIHR

Alberta Innovates Health Solutions

Snyder Institute for Chronic Diseases

Libin Cardiovascular Institute

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference54 articles.

1. GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes;Aglietti;Proc. Natl. Acad. Sci. U S A,2016

2. Use of a Shiga toxin (Stx)-enzyme-linked immunosorbent assay and immunoblot for detection and isolation of Stx-producing Escherichia coli from naturally contaminated beef;Atalla;J. Food Prot.,2000

3. NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5;Baker;Eur. J. Immunol.,2015

4. Structure, biological functions and applications of the AB5 toxins;Beddoe;Trends Biochem. Sci.,2010

5. Endoplasmic reticulum stress activates the inflammasome via NLRP3- and caspase-2-driven mitochondrial damage;Bronner;Immunity,2015

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