Defining and Targeting Adaptations to Oncogenic KRASG12C Inhibition Using Quantitative Temporal Proteomics-Reference-Cited by-同舟云学术

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Defining and Targeting Adaptations to Oncogenic KRASG12C Inhibition Using Quantitative Temporal Proteomics

Published:2020-03 Issue:13 Volume:30 Page:4584-4599.e4
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Santana-Codina Naiara^ORCID,Chandhoke Amrita Singh,Yu Qijia^ORCID,Małachowska Beata,Kuljanin Miljan,Gikandi Ajami,Stańczak Marcin,Gableske Sebastian,Jedrychowski Mark P.,Scott David A.,Aguirre Andrew J.,Fendler Wojciech,Gray Nathanael S.,Mancias Joseph D.^ORCID

Funder

Burroughs Wellcome Fund

Brigham and Women's Hospital

Sidney Kimmel Foundation

Dana-Farber Cancer Institute

Hale Family Center for Pancreatic Cancer Research

Canadian Institutes of Health Research

L’Oreal-UNESCO

Medical University of Lodz

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference89 articles.

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2. Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer;Alagesan;Clin. Cancer Res.,2015

3. An automated method for finding molecular complexes in large protein interaction networks;Bader;BMC Bioinformatics,2003

4. Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism;Biancur;Nat. Commun.,2017

5. The relevance of using 3D cell cultures, in addition to 2D monolayer cultures, when evaluating breast cancer drug sensitivity and resistance;Breslin;Oncotarget,2016

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1. Therapeutic targeting of Syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers;2024-08-08

2. Single-cell sensor analyses reveal signaling programs enabling Ras-G12C drug resistance;Nature Chemical Biology;2024-08-05

3. ZBTB11 Depletion Targets Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC;2024-05-21

4. Targeting KRASG12C in Non-Small-Cell Lung Cancer: Current Standards and Developments;Drugs;2024-04-16

5. Combining RAS^G12C(ON) inhibitor with SHP2 inhibition sensitises immune excluded lung tumours to immune checkpoint blockade: a strategy for turning cold tumours hot;2024-01-16

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