Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9

Author:

Hadders Michael A.,Bubeck Doryen,Roversi Pietro,Hakobyan Svetlana,Forneris Federico,Morgan B. Paul,Pangburn Michael K.,Llorca Oscar,Lea Susan M.,Gros Piet

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference57 articles.

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2. Structure of Complement C6 suggests a mechanism for initiation and unidirectional, sequential assembly of the Membrane Attack Complex (MAC);Aleshin;J. Biol. Chem.,2012

3. Proteolytic transformation of SC5b-9 into an amphiphilic macromolecule resembling the C5b-9 membrane attack complex of complement;Bhakdi;Immunology,1979

4. Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT;Blanc;Acta Crystallogr. D Biol. Crystallogr.,2004

5. Complement in human diseases: Lessons from complement deficiencies;Botto;Mol. Immunol.,2009

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