DLK signaling in axotomized neurons triggers complement activation and loss of upstream synapses

Author:

Asghari Adib Elham,Shadrach Jennifer L.,Reilly-Jankowiak Lauren,Dwivedi Manish K.,Rogers Abigail E.,Shahzad Shameena,Passino Ryan,Giger Roman J.,Pierchala Brian A.,Collins Catherine A.ORCID

Funder

Dr. Miriam and Sheldon G. Adelson Medical Research Foundation

National Institutes of Health

National Institute of Neurological Disorders and Stroke

Publisher

Elsevier BV

Reference82 articles.

1. Synaptic Plasticity on Motoneurons After Axotomy: A Necessary Change in Paradigm;Alvarez;Front. Mol. Neurosci.,2020

2. Displacement of synaptic terminals from regenerating motoneurons by microglial cells;Blinzinger;Z. Zellforsch. Mikrosk. Anat.,1968

3. Microglia: new roles for the synaptic stripper;Kettenmann;Neuron,2013

4. Spinal Motor Circuit Synaptic Plasticity after Peripheral Nerve Injury Depends on Microglia Activation and a CCR2 Mechanism;Rotterman;J. Neurosci.,2019

5. Synaptic density of axotomized hypoglossal motorneurons following pharmacological blockade of the microglial cell proliferation;Svensson;Exp. Neurol.,1993

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