Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer’s progression-Reference-Cited by-同舟云学术

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Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer’s progression

Published:2024-07 Issue:7 Volume:43 Page:114488
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Codocedo Juan F.,Mera-Reina Claudia,Bor-Chian Lin Peter,Fallen Paul B.,Puntambekar Shweta S.,Casali Brad T.,Jury-Garfe Nur,Martinez Pablo,Lasagna-Reeves Cristian A.,Landreth Gary E.

Publisher

Elsevier BV

Reference61 articles.

1. Microglial activation in early stages of amyloid beta protein deposition;Sasaki;Acta Neuropathol.,1997

2. TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy;Yuan;Neuron,2016

3. Microglia contribute to the propagation of Aβ into unaffected brain tissue;d’Errico;Nat. Neurosci.,2022

4. Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy;Wang;Nat. Commun.,2022

5. Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading;Jain;J. Exp. Med.,2023

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