Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids-Reference-Cited by-同舟云学术

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Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids

Published:2024-05 Issue:5 Volume:43 Page:114173
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Dhaliwal Navroop K.,Weng Octavia Yifang,Dong Xiaoxue,Bhattacharya Afrin,Ahmed Mai,Nishimura Haruka,Choi Wendy W.Y.,Aggarwal Aditi,Luikart Bryan W.,Shu Qiang,Li Xuekun,Wilson Michael D.,Moffat Jason,Wang Lu-Yang,Muffat Julien,Li Yun^ORCID

Funder

Simons Foundation

Canadian Institutes of Health Research

Publisher

Elsevier BV

Reference56 articles.

1. The neurology of mTOR;Lipton;Neuron,2014

2. Abnormal mTOR Activation in Autism;Winden;Annu. Rev. Neurosci.,2018

3. Phosphatase and tensin homolog (PTEN) gene mutations and autism: literature review and a case report of a patient with Cowden syndrome, autistic disorder, and epilepsy;Conti;J. Child Neurol.,2012

4. Genomic architecture of autism from comprehensive whole-genome sequence annotation;Trost;Cell,2022

5. PTEN-opathies: from biological insights to evidence-based precision medicine;Yehia;J. Clin. Invest.,2019

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