The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells-Reference-Cited by-同舟云学术

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The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells

Published:2018-05 Issue:7 Volume:23 Page:2107-2118
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Barazas Marco,Annunziato Stefano,Pettitt Stephen J.,de Krijger Inge,Ghezraoui Hind,Roobol Stefan J.,Lutz Catrin,Frankum Jessica,Song Fei Fei,Brough Rachel,Evers Bastiaan,Gogola Ewa,Bhin Jinhyuk,van de Ven Marieke,van Gent Dik C.,Jacobs Jacqueline J.L.,Chapman Ross,Lord Christopher J.,Jonkers Jos,Rottenberg Sven

Funder

Dutch Cancer Society

the Netherlands Organization for Scientific Research

Cancer Genomics Netherlands

National Roadmap Grant for Large-Scale Research Facilities

STW

Swiss National Science Foundation

Swiss Cancer League

European Union

ERC Synergy

Cancer Research UK

Breast Cancer Now

MRC

Wellcome core

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference54 articles.

1. Dynamic DNA binding, junction recognition and G4 melting activity underlie the telomeric and genome-wide roles of human CST;Bhattacharjee;Nucleic Acids Res.,2017

2. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection;Boersma;Nature,2015

3. 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers;Bouwman;Nat. Struct. Mol. Biol.,2010

4. A high-throughput functional complementation assay for classification of BRCA1 missense variants;Bouwman;Cancer Discov.,2013

5. Easy quantitative assessment of genome editing by sequence trace decomposition;Brinkman;Nucleic Acids Res.,2014

Cited by 126 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Shieldin and CST co-orchestrate DNA polymerase-dependent tailed-end joining reactions independently of 53BP1-governed repair pathway choice;Nature Structural & Molecular Biology;2024-09-03

2. PARP inhibitor resistance mechanisms and PARP inhibitor derived imaging probes;Expert Review of Anticancer Therapy;2024-09-03

3. PARPi, BRCA, and gaps: controversies and future research;Trends in Cancer;2024-09

4. 53BP1 loss elicits cGAS-STING-dependent antitumor immunity in ovarian and pancreatic cancer;Nature Communications;2024-08-06

5. ATM and 53BP1 regulate alternative end joining–mediated V(D)J recombination;Science Advances;2024-08-02

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