Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer-Reference-Cited by-同舟云学术

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Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer

Published:2017-01 Issue:3 Volume:18 Page:601-610
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Momcilovic Milica,Bailey Sean T.,Lee Jason T.,Fishbein Michael C.,Magyar Clara,Braas Daniel,Graeber Thomas,Jackson Nicholas J.,Czernin Johannes,Emberley Ethan,Gross Matthew,Janes Julie,Mackinnon Andy,Pan Alison,Rodriguez Mirna,Works Melissa,Zhang Winter,Parlati Francesco,Demo Susan,Garon Edward,Krysan Kostyantyn,Walser Tonya C.,Dubinett Steven M.,Sadeghi Saman,Christofk Heather R.,Shackelford David B.

Funder

CTSI and KL2 Translational Science Award

UCLA David Geffen School of Medicine

Kure It Cancer Research Foundation

STOP CANCER Foundation

DOD Lung Cancer Research Program Translational Research Partnership

NIH

CTSI

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference36 articles.

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3. Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides;Birsoy;Nature,2014

4. Environment impacts the metabolic dependencies of Ras-driven non-small cell lung cancer;Davidson;Cell Metab.,2016

5. Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy;Eng;Proc. Natl. Acad. Sci. USA,2016

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