A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure-Reference-Cited by-同舟云学术

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A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure

Published:2018-04 Issue:2 Volume:23 Page:327-336
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Frayling Timothy M.,Beaumont Robin N.,Jones Samuel E.,Yaghootkar Hanieh,Tuke Marcus A.,Ruth Katherine S.,Casanova Francesco,West Ben,Locke Jonathan,Sharp Seth,Ji Yingjie,Thompson William,Harrison Jamie,Etheridge Amy S.,Gallins Paul J.,Jima Dereje,Wright Fred,Zhou Yihui,Innocenti Federico,Lindgren Cecilia M.,Grarup Niels,Murray Anna,Freathy Rachel M.,Weedon Michael N.,Tyrrell Jessica,Wood Andrew R.^ORCID

Funder

European Research Council

Wellcome Trust and Royal Society

Diabetes UK

European Regional Development Fund

Diabetes Research and Wellness Foundation

Medical Research Council

Wellcome Trust

Li Ka Shing Foundation

National Institute for Health Research

Widenlife

NIH

Novo Nordisk Foundation

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference49 articles.

1. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes;Altshuler;Nat. Genet.,2000

2. Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity;Berglund;Endocrinology,2009

3. FGF21 regulates metabolism through adipose-dependent and -independent mechanisms;Bondurant;Cell Metab.,2017

4. FGF21 regulates metabolism and circadian behavior by acting on the nervous system;Bookout;Nat. Med.,2013

5. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma;Chambers;Nat. Genet.,2011

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