Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment
Author:
Funder
National Institutes of Health
National Cancer Institute
Publisher
Elsevier BV
Subject
General Biochemistry, Genetics and Molecular Biology
Reference67 articles.
1. c-myc amplification in hepatocellular carcinoma predicts unfavorable prognosis;Abou-Elella;Mod. Pathol.,1996
2. SHP2 drives adaptive resistance to ERK signaling inhibition in molecularly defined subsets of ERK-dependent tumors;Ahmed;Cell Rep.,2019
3. Oncogenic β-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice;Anson;J. Clin. Invest.,2012
4. Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection;Bard-Chapeau;Mol. Cell. Biol.,2006
5. Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis;Bard-Chapeau;Cancer Cell,2011
Cited by 34 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Advances in SHP2 tunnel allosteric inhibitors and bifunctional molecules;European Journal of Medicinal Chemistry;2024-09
2. Co-targeting SOS1 enhances the antitumor effects of KRASG12C inhibitors by addressing intrinsic and acquired resistance;Nature Cancer;2024-08-05
3. Therapeutic potential of targeting protein tyrosine phosphatases in liver diseases;Acta Pharmaceutica Sinica B;2024-08
4. G-CSF promotes the development of hepatocellular carcinoma by activating the PI3K/AKT/mTOR pathway in TAM;Aging;2024-07-01
5. Pharmacological inhibition of the Src homology phosphatase 2 confers partial protection in a mouse model of alcohol-associated liver disease;Biomedicine & Pharmacotherapy;2024-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3