Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer-Reference-Cited by-同舟云学术

Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer

Published:2023-04 Issue:4 Volume:42 Page:112324
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Mertens Sander,Huismans Maarten A.,Verissimo Carla S.,Ponsioen Bas,Overmeer Rene,Proost Natalie,van Tellingen Olaf,van de Ven Marieke,Begthel Harry,Boj Sylvia F.,Clevers Hans,Roodhart Jeanine M.L.,Bos Johannes L.,Snippert Hugo J.G.

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

KWF Kankerbestrijding

AACR

European Research Council

Engineering Research Centers

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference65 articles.

1. Therapeutic strategies to target RAS-mutant cancers;Ryan;Nat. Rev. Clin. Oncol.,2018

2. Targeting alterations in the RAF-MEK pathway;Yaeger;Cancer Discov.,2019

3. Ras oncogenes: split personalities;Karnoub;Nat. Rev. Mol. Cell Biol.,2008

4. BRAF mutants evade ERK-dependent feedback by different mechanisms that determine their sensitivity to pharmacologic inhibition;Yao;Cancer Cell,2015

5. Combined BRAF, EGFR, and MEK inhibition in patients with BRAF(V600E)-mutant colorectal cancer;Corcoran;Cancer Discov.,2018

Cited by 25 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Challenges in validation of combination treatment strategies for CRC using patient-derived organoids;Journal of Experimental & Clinical Cancer Research;2024-09-11

2. Exploring the potential of human intestinal organoids: Applications, challenges, and future directions;Life Sciences;2024-09

3. Applications of Organoids in Advancing Drug Discovery and Development;Journal of Pharmaceutical Sciences;2024-09

4. Establishment of the microscope incubation system and its application in evaluating tumor treatment effects through real-time live cellular imaging;Frontiers in Bioengineering and Biotechnology;2024-08-16

5. Quantification of Cytokine-Induced Cell Death in Human Colonic Organoids Using Live Fluorescence Microscopy;Journal of Visualized Experiments;2024-08-02