Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging-Reference-Cited by-同舟云学术

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Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging

Published:2019-04 Issue:2 Volume:27 Page:467-480.e6
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Janssens Georges E.,Lin Xin-Xuan,Millan-Ariño Lluís,Kavšek Alan,Sen Ilke,Seinstra Renée I.,Stroustrup Nicholas,Nollen Ellen A.A.,Riedel Christian G.

Funder

Spanish Ministry of Economy, Industry and Competitiveness

Centro de Excelencia Severo Ochoa

CERCA Programme/Generalitat de Catalunya

Glenn Foundation for Medical Research

European Research Council

Gooische Groningers

Ubbo Emmius Fonds

Swedish Research Council

COST

ICMC

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference115 articles.

1. Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal;Ayyadevara;Aging Cell,2005

2. HSF-1-mediated cytoskeletal integrity determines thermotolerance and life span;Baird;Science,2014

3. Heat shock protein 90 as a drug target: some like it hot;Banerji;Clin. Cancer Res.,2009

4. Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls;Bannister;Diabetes Obes. Metab.,2014

5. The DrugAge database of aging-related drugs;Barardo;Aging Cell,2017

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3. CUL-6/cullin ubiquitin ligase-mediated degradation of HSP-90 by intestinal lysosomes promotes thermotolerance;Cell Reports;2024-06

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