Histone chaperone FACT complex coordinates with HIF to mediate an expeditious transcription program to adapt to poorly oxygenated cancers

Author:

Shen Jialing,Yang Chunxue,Zhang Misty Shuo,Chin Don Wai-Ching,Chan For-FanORCID,Law Cheuk-Ting,Wang GengchaoORCID,Cheng Carol Lai-Hung,Chen Mengnuo,Wan Rebecca Ting-Chi,Wu Mengjie,Kuang Zhijian,Sharma Rakesh,Lee Terence Kin Wah,Ng Irene Oi-LinORCID,Wong Carmen Chak-Lui,Wong Chun-MingORCID

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

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4. Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma;Barone;Neuro Oncol.,2017

5. FACT facilitates transcription-dependent nucleosome alteration;Belotserkovskaya;Science,2003

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