Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism

Author:

Li Ni,Johnson David C.,Weinhold Niels,Kimber Scott,Dobbins Sara E.,Mitchell Jonathan S.,Kinnersley Ben,Sud Amit,Law Philip J.,Orlando Giulia,Scales Matthew,Wardell Christopher P.,Försti Asta,Hoang Phuc H.,Went Molly,Holroyd Amy,Hariri Fadi,Pastinen Tomi,Meissner Tobias,Goldschmidt Hartmut,Hemminki Kari,Morgan Gareth J.,Kaiser Martin,Houlston Richard S.

Funder

Myeloma UK

Bloodwise

Cancer Research UK

Bobby Moore Fund

Rosetrees Trust

Dietmar Hopp Foundation

German Ministry of Education and Science

Dietmar Hopp Stiftung

German Cancer Aid

German Research Council

Multiple Myeloma Research Foundation

Heinz Nixdorf Foundation

German Center for Neurodegenerative Disorders

CIHR

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference30 articles.

1. Familial risks and temporal incidence trends of multiple myeloma;Altieri;Eur. J. Cancer,2006

2. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response;Bertolotti;Nat. Cell Biol.,2000

3. Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk;Broderick;Nat. Genet.,2011

4. Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing;Chubb;J. Clin. Oncol.,2015

5. Interim Analysis Of The Mmrf Commpass Trial, a Longitudinal Study In Multiple Myeloma Relating Clinical Outcomes To Genomic and Immunophenotypic Profiles;Craig;Blood,2013

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