An Ancient Pseudoknot in TNF-α Pre-mRNA Activates PKR, Inducing eIF2α Phosphorylation that Potently Enhances Splicing-Reference-Cited by-同舟云学术

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An Ancient Pseudoknot in TNF-α Pre-mRNA Activates PKR, Inducing eIF2α Phosphorylation that Potently Enhances Splicing

Published:2017-07 Issue:1 Volume:20 Page:188-200
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Namer Lise Sarah,Osman Farhat,Banai Yona,Masquida Benoît,Jung Rodrigo,Kaempfer Raymond

Funder

Israel Science Foundation

German Research Foundation (DFG)

University of Strasbourg

CNRS

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference36 articles.

1. Superantigen antagonist protects against lethal shock and defines a new domain for T-cell activation;Arad;Nat. Med.,2000

2. Human interferon-γ mRNA autoregulates its translation through a pseudoknot that activates the interferon-inducible protein kinase PKR;Ben-Asouli;Cell,2002

3. Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR;Bevilacqua;Biochemistry,1996

4. Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes;Bevilacqua;Biochemistry,1998

5. A selective inhibitor of eIF2α dephosphorylation protects cells from ER stress;Boyce;Science,2005

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1. RNA recognition by PKR during DNA virus infection;Journal of Medical Virology;2024-01-29

2. RNA Activators of Stress Kinase PKR within Human Genes That Control Splicing or Translation Create Novel Targets for Hereditary Diseases;International Journal of Molecular Sciences;2024-01-22

3. Signaling plasticity in the integrated stress response;Frontiers in Cell and Developmental Biology;2023-12-07

4. Positive Regulation of Splicing of Cellular and Viral mRNA by Intragenic RNA Elements That Activate the Stress Kinase PKR, an Antiviral Mechanism;Genes;2023-04-26

5. HIV co-opts a cellular antiviral mechanism, activation of stress kinase PKR by its RNA, to enable splicing of rev/tat mRNA;Cell & Bioscience;2023-02-11

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