E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia-Reference-Cited by-同舟云学术

E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia

Published:2017-02 Issue:8 Volume:18 Page:2007-2017
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Benini Monica,Fortuni Silvia,Condò Ivano,Alfedi Giulia,Malisan Florence,Toschi Nicola,Serio Dario,Massaro Damiano Sergio,Arcuri Gaetano,Testi Roberto,Rufini Alessandra

Funder

European Research Council

Telethon, Italy

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference63 articles.

1. The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues;Al-Mahdawi;Hum. Mol. Genet.,2008

2. Friedreich’s ataxia;Alper;Pediatr. Neurol.,2003

3. Fixing frataxin: ‘ironing out’ the metabolic defect in Friedreich’s ataxia;Anzovino;Br. J. Pharmacol.,2014

4. New insights into ubiquitin E3 ligase mechanism;Berndsen;Nat. Struct. Mol. Biol.,2014

5. BAG-6, a jack of all trades in health and disease;Binici;Cell. Mol. Life Sci.,2014

Cited by 36 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Regulation of the Disease-Causing Gene FXN;Cells;2024-06-15

2. An RNA-seq study in Friedreich ataxia patients identified hsa-miR-148a-3p as a putative prognostic biomarker of the disease;Human Genomics;2024-05-22

3. RNF126-mediated ubiquitination of FSP1 affects its subcellular localization and ferroptosis;Oncogene;2024-03-21

4. Frataxin inhibits the sensitivity of the myocardium to ferroptosis by regulating iron homeostasis;Free Radical Biology and Medicine;2023-08

5. E3 ubiquitin ligases and deubiquitinases in bladder cancer tumorigenesis and implications for immunotherapies;Frontiers in Immunology;2023-07-11