Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents-Reference-Cited by-同舟云学术

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Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents

Published:2015-12 Issue:11 Volume:13 Page:2353-2361
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Wang Pu,Wu Jing,Ma Shenghong,Zhang Lei,Yao Jun,Hoadley Katherine A.,Wilkerson Matthew D.,Perou Charles M.,Guan Kun-Liang,Ye Dan,Xiong Yue

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference31 articles.

1. Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA;Aas;Nature,2003

2. IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours;Amary;J. Pathol.,2011

3. Successful chemotherapy for recurrent malignant oligodendroglioma;Cairncross;Ann. Neurol.,1988

4. Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402;Cairncross;J. Clin. Oncol.,2013

5. Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH;Cairncross;J. Clin. Oncol.,2014

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5. Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity;DNA Repair;2024-08

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