Highly diastereo- and enantioselective catalytic synthesis of the bis-tetrahydrofuran alcohol of Brecanavir and Darunavir-Reference-Cited by-同舟云学术

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Highly diastereo- and enantioselective catalytic synthesis of the bis-tetrahydrofuran alcohol of Brecanavir and Darunavir

Published:2008-09 Issue:17 Volume:19 Page:2015-2019
ISSN:0957-4166
Container-title:Tetrahedron: Asymmetry
language:en
Short-container-title:Tetrahedron: Asymmetry

Author:

Black David M.,Davis Roman,Doan Brian D.,Lovelace Tom C.,Millar Alan,Toczko Jennifer F.,Xie Shiping

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

Reference34 articles.

1. Design of HIV Protease Inhibitors Targeting Protein Backbone: An Effective Strategy for Combating Drug Resistance

2. Bis-Tetrahydrofuran: a Privileged Ligand for Darunavir and a New Generation of HIV Protease Inhibitors That Combat Drug Resistance

3. Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Proteases by GW0385 and Other Arylsulfonamides

4. Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: The discovery of GW0385

5. Structure-based design of non-peptide HIV protease inhibitors

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1. Carbonylchemie;Organische Synthesemethoden;2023

2. An Efficient Synthesis of the Bicyclic Darunavir Side Chain Using Chemoenzymatic Catalysis;Organic Process Research & Development;2022-02-18

3. Sustainable Synthetic Strategies for the Preparation of Low Molecular Weight Drugs by Biotech Routes;Journal of the Brazilian Chemical Society;2022

4. Catalytic Asymmetric Synthesis of Hexahydro-furofuran-3-ol and Its Pyran Derivatives;Organic Letters;2021-04-19

5. Ru-catalyzed asymmetric transfer hydrogenation of α-acyl butyrolactone via dynamic kinetic resolution: Asymmetric synthesis of bis-THF alcohol intermediate of darunavir;Tetrahedron Letters;2021-03

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