An integrin beta4-EGFR unit promotes hepatocellular carcinoma lung metastases by enhancing anchorage independence through activation of FAK

An integrin beta4-EGFR unit promotes hepatocellular carcinoma lung metastases by enhancing anchorage independence through activation of FAK–AKT pathway

Published:2016-06 Issue:1 Volume:376 Page:188-196
ISSN:0304-3835
Container-title:Cancer Letters
language:en
Short-container-title:Cancer Letters

Author:

Leng Chao,Zhang Zhan-guo,Chen Wei-xun,Luo Hong-ping,Song Jia,Dong Wei,Zhu Xuan-ru,Chen Xiao-ping,Liang Hui-fang,Zhang Bi-xiang

Funder

The State Key Project on Infection Diseases of China

The National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference41 articles.

1. Emerging trends in hepatocellular carcinoma incidence and mortality;Njei;Hepatology,2015

2. Management of hepatocellular carcinoma: an update;Bruix;Hepatology,2011

3. Sorafenib in advanced hepatocellular carcinoma;Llovet;N. Engl. J. Med,2008

4. Prognosis of hepatocellular carcinoma: comparison of 7 staging systems in an American cohort;Marrero;Hepatology,2005

5. Tumor metastasis: molecular insights and evolving paradigms;Valastyan;Cell,2011

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