APR-246 (PRIMA-1 MET ) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines-Reference-Cited by-同舟云学术

APR-246 (PRIMA-1 MET ) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines

Published:2016-06 Issue:2 Volume:375 Page:313-322
ISSN:0304-3835
Container-title:Cancer Letters
language:en
Short-container-title:Cancer Letters

Author:

Deben Christophe^ORCID,Lardon Filip,Wouters An,Op de Beeck Ken,Van den Bossche Jolien,Jacobs Julie,Van Der Steen Nele,Peeters Marc,Rolfo Christian^ORCID,Deschoolmeester Vanessa,Pauwels Patrick

Funder

Agency for Innovation by Science and Technology, Flanders

Research Foundation Flanders

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference41 articles.

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2. Mutant p53 reactivation by small molecules makes its way to the clinic;Bykov;FEBS Lett,2014

3. APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma;Liu;Gut,2015

4. APR-246 exhibits anti-leukemic activity and synergism with conventional chemotherapeutic drugs in acute myeloid leukemia cells;Ali;Eur. J. Haematol,2011

5. APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells;Mohell;Cell Death Dis,2015

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