A novel HDAC6 inhibitor Tubastatin A: Controls HDAC6-p97/VCP-mediated ubiquitination-autophagy turnover and reverses Temozolomide-induced ER stress-tolerance in GBM cells

Author:

Li Zong-yang,Zhang Ce,Zhang Yuan,Chen Lei,Chen Bao-dong,Li Qing-zhong,Zhang Xie-jun,Li Wei-ping

Funder

Research Fund from Shenzhen Key Laboratory of Neurosurgery

Shenzhen Science and Technology Program

Postdoctoral Science Foundation of China

Natural Science Foundation of Guangdong

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference36 articles.

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3. ABCB1, ABCG2, and PTEN determine the response of glioblastoma to temozolomide and ABT-888 therapy;Lin;Clin. Cancer Res.,2014

4. The synergistic effect of combination temozolomide and chloroquine treatment is dependent on autophagy formation and p53 status in glioma cells;Lee;Cancer Lett.,2015

5. Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models;Chen;Cancer Lett.,2011

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