Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors

Author:

Zhang Ming,Singh Ratnakar,Peng Shaohua,Mazumdar Tuhina,Sambandam Vaishnavi,Shen Li,Tong Pan,Li Lerong,Kalu Nene N.,Pickering Curtis R.,Frederick Mitchell,Myers Jeffrey N.,Wang Jing,Johnson Faye M.

Funder

NIH/NCI

HPV-Related Cancers Moon Shot Program

Oropharynx Discovery Programs

Natural Science Foundation of Shanghai

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference72 articles.

1. Broad Institute Picard. http://broadinstitute.github.io/picard/.

2. Mutation Analysis (MutSig 2CV v3.1);Broad Institute TCGA Genome Data Analysis Center,2016

3. LATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosis;Abe;FEBS Lett.,2006

4. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1;Agrawal;Science,2011

5. A novel mechanism for activation of Aurora-A kinase by Ajuba;Bai;Gene,2014

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