Development and in vitro validation of anti-mesothelin biobodies that prevent CA125/Mesothelin-dependent cell attachment

Author:

Bergan Lindsay,Gross Jennifer A.,Nevin Barry,Urban Nicole,Scholler Nathalie

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference42 articles.

1. Cancer Facts & Figures 2007, American Cancer Society http://www.cancer.org/downloads/STT/CAFF2007PWSecured.pdf 2006.

2. Key Statistics About Ovarian Cancer, American Cancer Society http://www.cancer.org 2006.

3. Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion;Rump;J. Biol. Chem.,2004

4. Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors;Gubbels;Mol. Cancer.,2006

5. Development of a CA125-mesothelin cell adhesion assay as a screening tool for biologics discovery;Scholler;Cancer Lett.,2007

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