Structural basis for potent inhibition of the Aurora kinases and a T315I multi-drug resistant mutant form of Abl kinase by VX-680

Author:

Cheetham G.M.T.,Charlton P.A.,Golec J.M.C.,Pollard J.R.

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference31 articles.

1. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains;Hanks;Science,1998

2. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells;Druker;Nat. Med.,1995

3. Inhibition of the Abl protein-tyro sine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative;Buchdunger;Cancer Res.,1996

4. The biology of chronic myeloid leukemia;Faderl;N. Engl. J. Med.,1999

5. The GIST of Targeted Cancer Therapy: A Tumour (Gastrointestinal Stromal Tumour), a Mutated Gene (c-kit), and a Molecular Inhibitor (STI571). Ann. Surg. Oncol. 9 (2002) 831–839.

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