Frequent rearrangements and amplification of the CDX2 homeobox gene in human sporadic colorectal cancers with chromosomal instability

Author:

Subtil Clément,Guérin Eric,Schneider Anne,Chenard Marie-Pierre,Martin Elisabeth,Domon-Dell Claire,Duluc Isabelle,Brabletz Thomas,Kedinger Michèle,Duclos Bernard,Gaub Marie-Pierre,Freund Jean-Noël

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference22 articles.

1. Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma;Ee;Am. J. Pathol.,1995

2. The homeobox intestinal differentiation factor CDX2 is selectively expressed in gastrointestinal adenocarcinomas;Kaimaktchiev;Mod. Pathol.,2004

3. Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis;Mallo;Int. J. Cancer,1997

4. Loss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colon;Hinoi;Am. J. Pathol.,2001

5. Downregulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: active role of the tumor environment for malignant tumor progression;Brabletz;Cancer Res.,2004

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