Proteolysis-targeting chimeras: A promising technique in cancer therapy for gaining insights into tumor development
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Oncology
Reference136 articles.
1. Protein quality control and elimination of protein waste: the role of the ubiquitin-proteasome system;Amm;Biochim. Biophys. Acta,2014
2. Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation;Sakamoto;Proc. Natl. Acad. Sci. Unit. States Am.,2001
3. Small molecules destabilize cIAP1 by activating auto-ubiquitylation;Sekine;J. Biol. Chem.,2008
4. Catalytic in vivo protein knockdown by small-molecule PROTACs;Bondeson;Nat. Chem. Biol.,2015
5. Drug development. Phthalimide conjugation as a strategy for in vivo target protein degradation;Winter;Science,2015
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Anticancer Therapy with Proteolysis-targeting Chimeras [PROTACs] Targeting Towards the Tumor-microenvironment: Development, Current State and Prospects;Current Cancer Therapy Reviews;2024-05-14
2. Potential of the nanoplatform and PROTAC interface to achieve targeted protein degradation through the Ubiquitin–Proteasome system;European Journal of Medicinal Chemistry;2024-03
3. Could Targeting NPM1c+ Misfolding Be a Promising Strategy for Combating Acute Myeloid Leukemia?;International Journal of Molecular Sciences;2024-01-09
4. Proteolysis-targeting chimeras in biotherapeutics: Current trends and future applications;European Journal of Medicinal Chemistry;2023-09
5. Current strategies for improving limitations of proteolysis targeting chimeras;Chinese Chemical Letters;2023-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3