KIAA1199 promotes sorafenib tolerance and the metastasis of hepatocellular carcinoma by activating the EGF/EGFR-dependent epithelial-mesenchymal transition program

Author:

Xu Yanmin,Xu Huailong,Li Mingyuan,Wu Hua,Guo Yanhe,Chen Jun,Shan Juanjuan,Chen Xuejiao,Shen Junjie,Ma Qinghua,Liu Jingxia,Wang Meiling,Zhao Wenxu,Hong Juan,Qi Yanan,Yao Chao,Zhang Qianzhen,Yang Zhi,Qian Cheng,Li JianmingORCID

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference35 articles.

1. Global cancer statistics;Torre;CA A Cancer J. Clin.,2015

2. Imagiological diagnosis of gastrointestinal diseases - diagnostic criteria of hepatocellular carcinoma;Boal Carvalho;GE Port J Gastroenterol,2015

3. Integrated multi-omics data analysis identifying novel drug sensitivity-associated molecular targets of hepatocellular carcinoma cells;Yildiz;Oncol Lett,2018

4. Sorafenib in advanced hepatocellular carcinoma;Palmer;N. Engl. J. Med.,2008

5. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5;Liu;Cancer Res.,2006

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