Compensatory activation of Akt in response to mTOR and Raf inhibitors – A rationale for dual-targeted therapy approaches in neuroendocrine tumor disease
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Oncology
Reference36 articles.
1. The diagnosis and medical management of advanced neuroendocrine tumors;Kaltsas;Endocr. Rev.,2004
2. Natural history of neuroendocrine enteropancreatic tumors;Mignon;Digestion,2000
3. Cotargeting survival signaling pathways in cancer;Grant;J. Clin. Invest.,2008
4. Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia;Steelman;Leukemia,2008
5. MTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt;O’Reilly;Cancer Res.,2006
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