An MDM2 degrader shows potent cytotoxicity to MDM2-overexpressing acute lymphoblastic leukemia cells with minimal toxicity to normal cells/tissues
Author:
Funder
Emory University School of Medicine
Andrew McDonough B+ Foundation
Alex's Lemonade Stand Foundation for Childhood Cancer
University of Tennessee Health Science Center
Publisher
Elsevier BV
Reference39 articles.
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2. The human MDM-2 oncogene is overexpressed in leukemias;Bueso-Ramos;Blood,1993
3. Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene;Zhou;Blood,1995
4. Overexpression of MDM2 in acute childhood lymphoblastic leukemia;Gustafsson;Pediatr. Hematol. Oncol.,1998
5. Incidence and prognostic significance of MDM2 oncoprotein overexpression in relapsed childhood acute lymphoblastic leukemia;Zhou;Leukemia,2000
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