Downregulation of Epidermal Growth Factor Receptor in hepatocellular carcinoma facilitates Transforming Growth Factor-β-induced epithelial to amoeboid transition

Author:

López-Luque Judit,Bertran Esther,Crosas-Molist Eva,Maiques Oscar,Malfettone Andrea,Caja Laia,Serrano Teresa,Ramos Emilio,Sanz-Moreno Victoria,Fabregat Isabel

Funder

Ministry of Science, Innovation and Universities, Spain

FEDER funds/Development Fund

National Biomedical Research Institute on Liver and Gastrointestinal Diseases

Instituto de Salud Carlos III, Spain

REA

Cancer Research UK (CRUK)

Royal Society

Fundación Ramón Areces

Generalitat de Catalunya

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference50 articles.

1. Hepatocellular carcinoma;Llovet;Nat Rev Dis Primer,2016

2. Inhibition of DNA synthesis in rat hepatocytes by platelet-derived type beta transforming growth factor;Carr;Cancer Res.,1986

3. Apoptosis induced by transforming growth factor-beta in fetal hepatocyte primary cultures: involvement of reactive oxygen intermediates;Sánchez;J. Biol. Chem.,1996

4. Induction of epithelial-mesenchymal transition by transforming growth factor β;Moustakas;Semin. Cancer Biol.,2012

5. The epidermal growth factor receptor pathway: a model for targeted therapy;Scaltriti;Clin. Cancer Res.,2006

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