Cullin7 enhances resistance to trastuzumab therapy in Her2 positive breast cancer via degrading IRS-1 and downregulating IGFBP-3 to activate the PI3K/AKT pathway-Reference-Cited by-同舟云学术

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Cullin7 enhances resistance to trastuzumab therapy in Her2 positive breast cancer via degrading IRS-1 and downregulating IGFBP-3 to activate the PI3K/AKT pathway

Published:2019-11 Issue: Volume:464 Page:25-36
ISSN:0304-3835
Container-title:Cancer Letters
language:en
Short-container-title:Cancer Letters

Author:

Qiu Ni,He Yu-fang,Zhang Si-ming,Zhan Yong-tao,Han Guo-dong,Jiang Ming,He Wei-xing,Zhou Jie,Liang Hong-ling,Ao Xiang,Xia Hao-ming,Li Jia,Yang Yu-yang,He Zhi-min,Zou Zheng-zhi,Li Hong-sheng

Funder

Natural Science Foundation of Guangdong Province

Program of Bureau of Education of Guangzhou Municipality

Program of Bureau of Health of Guangzhou Municipality

National Natural Science Foundation of China

Scientific and Technological Planning Project of Guangzhou City

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference55 articles.

1. Therapeutic implications of cellular heterogeneity and plasticity in breast cancer;Brooks;Cell Stem Cell,2015

2. Molecular biology in breast cancer: intrinsic subtypes and signaling pathways;Eroles;Cancer Treat Rev.,2012

3. Breast tumor heterogeneity: source of fitness, hurdle for therapy;Koren;Mol. Cell,2015

4. Human epidermal growth factor receptor 2 (HER2)-positive and hormone receptor-positive breast cancer: new insights into molecular interactions and clinical implications;Montemurro;Ann. Oncol. Off. J. Eur. Soc. Med. Oncol.,2013

5. Clinical implications of the intrinsic molecular subtypes of breast cancer;Prat;Breast,2015

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Extracellular Interactors of the IGF System: Impact on Cancer Hallmarks and Therapeutic Approaches;International Journal of Molecular Sciences;2024-05-29

2. Single-Cell Analysis Reveals Adipose Cancer-Associated Fibroblasts Linked to Trastuzumab Resistance in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer;Science of Advanced Materials;2023-10-01

3. Preclinical and Basic Research Strategies for Overcoming Resistance to Targeted Therapies in HER2-Positive Breast Cancer;Cancers;2023-04-30

4. Identification of Breast Cancer Subtypes by Integrating Genomic Analysis with the Immune Microenvironment;ACS Omega;2023-03-21

5. Cancerous inhibitor of protein phosphatase 2A enhances chemoresistance of gastric cancer cells to oxaliplatin;World Journal of Gastrointestinal Oncology;2023-02-15

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