Partial deficiency of DNA-PKcs increases ionizing radiation-induced mutagenesis and telomere instability in human cells

Author:

Zhang Ying,Zhou Junqing,Cao Xiaofan,Zhang Qinming,Lim Chang U.K.,Ullrich Robert L.,Bailey Susan M.,Liber Howard L.

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference53 articles.

1. Endogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancer;Vilenchik;Proc. Natl. Acad. Sci. USA,2003

2. ATM and related protein kinases: safeguarding genome integrity;Shiloh;Nat. Rev. Cancer,2003

3. Two genetic hits (more or less) to cancer;Knudson;Nat. Rev. Cancer,2001

4. Haploinsufficiency for tumour suppressor genes: when you don’t need to go all the way;Santarosa;Biochim. Biophys. Acta.,2004

5. Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation;DeWeese;Proc. Natl. Acad. Sci. USA,1998

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