RNF12 promotes p53-dependent cell growth suppression and apoptosis by targeting MDM2 for destruction
Author:
Funder
National Natural Science Foundation of China
Shanghai Municipal Science and Technology Commission
Publisher
Elsevier BV
Subject
Cancer Research,Oncology
Reference19 articles.
1. Modes of p53 regulation;Kruse;Cell,2009
2. p53 and human cancer: the first ten thousand mutations;Hainaut;Adv. Cancer Res,2000
3. The INK4a/ARF network in tumour suppression;Sherr;Nat. Rev. Mol. Cell Biol,2001
4. Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation;Stommel;EMBO J.,2004
5. Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation;Itahana;Cancer Cell,2007
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