Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN-Reference-Cited by-同舟云学术

Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN

Published:2011-09 Issue:1 Volume:308 Page:71-80
ISSN:0304-3835
Container-title:Cancer Letters
language:en
Short-container-title:Cancer Letters

Author:

Heo Ji Young,Kim Hyun Jung,Kim Sung-Moo,Park Kyung-Ran,Park Sang-Yoon,Kim Seong Won,Nam Dongwoo,Jang Hyeung-Jin,Lee Seok-Geun,Ahn Kyoo Seok,Kim Sung-Hoon,Shim Bum Sang,Choi Seung-Hoon,Ahn Kwang Seok

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference42 articles.

1. Discovery of embelin as a cell-permeable small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database;Nikolovska-Coleska;J. Med. Chem.,2004

2. Embelin an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products;Ahn;Mol. Pharmacol.,2007

3. Effect of the XIAP inhibitor embelin on TRAIL-induced apoptosis of pancreatic cancer cells;Mori;J. Surg. Res.,2007

4. The XIAP inhibitor embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP;Siegelin;Neurochem. Int.,2009

5. Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis;Dai;Cancer Res.,2009

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