All-trans retinoic acid exerts selective anti-FLT3-ITD acute myeloid leukemia efficacy through downregulating Chk1 kinase

Author:

Wang Wenliang,Jiang Zongru,Wang Li,Wang Aoli,Liu Juan,Chen Cheng,Yu Kailin,Zou Fengming,Wang Wenchao,Liu Jing,Liu Qingsong

Funder

National Natural Science Foundation of China

Natural Science Foundation of Anhui Province

Science and Technology Major Projects of Anhui Province

China Postdoctoral Science Foundation

Frontier Science Key Research Program of CAS

Innovative Program of Development Foundation of Hefei Center for Physical Science and Technology

CASHIPS

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference34 articles.

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2. Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients;Kihara;Leukemia,2014

3. Absence of the wild-type Allele predicts poor prognosis in adult de Novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B Study1;Whitman;Cancer Res.,2001

4. Inactivation of PBX3 and HOXA9 by down-regulating H3K79 methylation represses NPM1-mutated leukemic cell survival;Zhang;Theranostics,2018

5. NPM1 mutant mediated PML delocalization and stabilization enhances autophagy and cell survival in leukemic cells;Zou;Theranostics,2017

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