The poly(ADP-ribose) polymerase inhibitor olaparib induces up-regulation of death receptors in primary acute myeloid leukemia blasts by NF-κB activation

Author:

Faraoni Isabella,Aloisio Francesca,De Gabrieli Antonio,Consalvo Maria Irno,Lavorgna Serena,Voso Maria Teresa,Lo-Coco Francesco,Graziani Grazia

Funder

Associazione Italiana per la Ricerca sul Cancro, Italy

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference56 articles.

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2. Treatment of relapsed/refractory acute myeloid leukemia;Bose;Curr. Treat. Options Oncol.,2017

3. BRCA1, PARP1 and γH2AX in acute myeloid leukemia: role as biomarkers of response to the PARP inhibitor olaparib;Faraoni;Biochim. Biophys. Acta,2015

4. Lynparza [package Insert]. DE;AstraZeneca Pharmaceuticals,2014

5. Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer, N. Engl;Ledermann;J. Med.,2012

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