Murine Pten−/− T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and γc/TCR signals for thymic exit
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Oncology
Reference47 articles.
1. Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase;Webb;J. Immunol.,2005
2. Deficient T cell fate specification in mice with an induced inactivation of Notch1;Radtke;Immunity,1999
3. The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling;Hagenbeek;J. Exp. Med.,2004
4. T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus;Hagenbeek;Leukemia,2008
5. Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia;Weerkamp;Leukemia,2006
Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Resistance mechanism to Notch inhibition and combination therapy in human T-cell acute lymphoblastic leukemia;Blood Advances;2023-10-13
2. Role of chemokines in T-cell acute lymphoblastic Leukemia: From pathogenesis to therapeutic options;International Immunopharmacology;2023-08
3. Resistance mechanism to Notch inhibition and combination therapy in human T cell acute lymphoblastic leukemia;2023-01-24
4. Resistance mechanism to Notch inhibition and combination therapy in human T cell acute lymphoblastic leukemia;2022-12-23
5. PTEN in Regulating Hematopoiesis and Leukemogenesis;Cold Spring Harbor Perspectives in Medicine;2019-11-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3