A review of PCSK9 inhibition and its effects beyond LDL receptors
Author:
Publisher
Elsevier BV
Subject
Cardiology and Cardiovascular Medicine,Nutrition and Dietetics,Endocrinology, Diabetes and Metabolism,Internal Medicine
Reference65 articles.
1. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia;Abifadel;Nat Genet,2003
2. Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk;Humphries;J Med Genet,2006
3. Sequence Variations in PCSK9, Low LDL, and Protection against Coronary Heart Disease;Cohen;N Engl J Med,2006
4. Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9;Rashid;Proc Natl Acad Sci U S A,2005
5. Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters;Dong;J Lipid Res,2010
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