Real-world data to assess changes in low-density lipoprotein cholesterol and predicted cardiovascular risk after ezetimibe discontinuation post reporting of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression trial

Author:

Bays Harold E.,Patel Mehul D.,Mavros Panagiotis,Ramey Dena R.,Tomassini Joanne E.,Tershakovec Andrew M.,Baxter Carl A.

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine,Nutrition and Dietetics,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference40 articles.

1. Biomarkers and surrogate endpoints in clinical trials;Fleming;Stat Med,2012

2. National Lipid Association Annual Summary of Clinical Lipidology 2016;Bays;J Clin Lipidol,2016

3. FDA. Guidance for Industry: Evidence-based review system for the scientific evaluation of health claims – final. Available at: http://www.fda.gov/Food/GuidanceRegulation/GuidanceDocumentsRegulatoryInformation/LabelingNutrition/ucm073332.htm. Accessed December 23, 2016.

4. FDA. Biomarkers used as outcomes in development of FDA-approved therapeutics (October 2007–December 2015). Available at: http://www.fda.gov/drugs/developmentapprovalprocess/drugdevelopmenttoolsqualificationprogram/ucm483052.htm. Accessed December 23, 2016.

5. Attenuation of rate of change in carotid intima-media thickness by lipid-modifying drugs;Peters;Am J Cardiovasc Drugs,2011

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