Comparison of the 9-anilinoacridines o-AMSA (4'-(acridin-9-ylamino)-2'-methoxymethanesulfonanilide) and m-AMSA (4'-(acridin-9-ylamino)-3'- methoxymethanesulfonanilide). A molecular mechanics, dynamics and semiempirical molecular orbital study-Reference-Cited by-同舟云学术

Comparison of the 9-anilinoacridines o-AMSA (4'-(acridin-9-ylamino)-2'-methoxymethanesulfonanilide) and m-AMSA (4'-(acridin-9-ylamino)-3'- methoxymethanesulfonanilide). A molecular mechanics, dynamics and semiempirical molecular orbital study

Published:1991-12 Issue: Volume:251 Page:283-296
ISSN:0166-1280
Container-title:Journal of Molecular Structure: THEOCHEM
language:en
Short-container-title:Journal of Molecular Structure: THEOCHEM

Author:

Smith Douglas A.,Gilbert Matthew J.,Ulmer Charles W.,Cheatham Steve F.

Publisher

Elsevier BV

Subject

Physical and Theoretical Chemistry,Condensed Matter Physics,Biochemistry

Reference27 articles.

1. Evaluation of intensive postremission chemotherapy for adults with acute nonlymphocytic leukemia using high-dose cytosine arabinoside with L-asparaginase and amsacrine with etoposide.

2. Potential antitumor agents. 16. 4'-(Acridin-9-ylamino)methanesulfonanilides

3. Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring

4. Potential antitumor agents. 35. Quantitative relationships between antitumor (L1210) potency and DNA binding for 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) analogs

5. Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The semiempirical and DFT methods in studies on geometry and energetics of AMSA isomers: comparison of m-AMSA and o-AMSA properties;Journal of Molecular Structure: THEOCHEM;2004-08

2. Ab initio calculations and molecular mechanics (MM3) force field development for sulfonamide and its alkyl derivatives;Journal of Molecular Structure: THEOCHEM;1997-08

3. Structural studies of aromatic amines and the dna intercalating compoundsm-amsa ando-amsa: Comparison of mndo, am1, and pm3 to experimental andab initio results;Journal of Computational Chemistry;1992-06