The structure of ibuprofen bound to cyclooxygenase-2-Reference-Cited by-同舟云学术

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The structure of ibuprofen bound to cyclooxygenase-2

Published:2015-01 Issue:1 Volume:189 Page:62-66
ISSN:1047-8477
Container-title:Journal of Structural Biology
language:en
Short-container-title:Journal of Structural Biology

Author:

Orlando Benjamin J.,Lucido Michael J.,Malkowski Michael G.

Funder

National Institutes of Health

National Institute of General Medical Sciences

National Science Foundation

National Center for Research Resources

Publisher

Elsevier BV

Subject

Structural Biology

Reference33 articles.

1. PHENIX: a comprehensive Python-based system for macromolecular structure solution;Adams;Acta Crystallogr. D Biol. Crystallogr.,2010

2. Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1;Bhattacharyya;J. Biol. Chem.,1996

3. Structural and functional basis of cyclooxygenase inhibition;Blobaum;J. Med. Chem.,2007

4. MolProbity: all-atom contacts and structure validation for proteins and nucleic acids;Davis;Nucleic Acids Res.,2007

5. Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer;Dong;J. Biol. Chem.,2011

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