Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD+-dependent DNA ligase A
Author:
Funder
Department of Science and Technology, Ministry of Science and Technology, India
Council of Scientific and Industrial Research, India
Publisher
Elsevier BV
Subject
Structural Biology
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1. From bacteria to biomedicine: Developing therapies exploiting NAD+ metabolism;Bioorganic Chemistry;2024-01
2. Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD+-dependent DNA ligase A (MtbLigA) are important for the initial steps of nick-sealing activity;Acta Crystallographica Section D Structural Biology;2021-05-14
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