Preparation of rat brain membranes greatly enriched with either type-I-delta or type-II-delta opiate binding sites using site directed alkylating agents: Evidence for a two-site allosteric model

Author:

Rothman Richard B,Bowen Wayne D,Bykov Victor,Schumacher Uwe K,Pert Candace B,Jacobson Arthur E,Burke Terrence R,Rice Kenner C

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Endocrine and Autonomic Systems,Neurology,Endocrinology,General Medicine

Reference31 articles.

1. 3H-leu5-enkephalin specific binding to synaptic membranes: comparison with 3H-dihydromorphine and 3H-naloxone;Law;Res. Comm. Chem. Path. Pharmacol.,1978

2. Multiple opiate receptors: enkephalins and morphine bind to receptors of different specificity;Chang;J. Biol. Chem.,1979

3. Discrimination of three opiate receptor binding sites with the use of a computerized curve fitting technique;Pfeiffer;Mol. Pharmacol.,1982

4. Characterization of opioid receptors in nervous tissue;Kosterlitz,1980

5. Morphine allosterically modulates the binding of [3H]leucine enkephalin to a particulate fraction of rat brain;Rothman;Mol. Pharmacol.,1982

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