Metabolism and pharmacokinetics of TRH and an analogue with enhanced neuropharmacological potency
Author:
Publisher
Elsevier BV
Subject
Cellular and Molecular Neuroscience,Endocrine and Autonomic Systems,Neurology,Endocrinology,General Medicine
Reference28 articles.
1. Regulation of degradation of thyrotropin releasing hormone by thyroid hormones;Bauer;Nature,1976
2. Degradation of hypothalamic hormones;Bauer;Naunyn-Schmiedeberg's Arch. Pharmacol.,1977
3. An analogue of thyrotropin releasing hormone with improved biological stability both in vitro and in vivo;Brewster;Biochem. Pharmacol.,1980
4. Modification of the proline residue of TRH enhances biological activity and inhibits degradation;Brewster;Euro. J. Pharmacol.,1980
5. TRH degradation rates vary widely between different animal species;Brewster;Biochem. Pharmacol.,1981
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1. Comparative conformation-activity relationships for hormonally- and centrally-acting TRH analogues;International Journal of Peptide and Protein Research;2009-01-12
2. Brain receptor binding characteristics and pharmacokinetics of JTP-2942, a novel thyrotropin-releasing hormone (TRH) analogue;Life Sciences;1999-10
3. A radioimmunoassay for TA-0910, a new metabolically stable thyrotrophin-releasing hormone analogue;Journal of Pharmaceutical and Biomedical Analysis;1994-06
4. Synthesis of Analogues of Thyrotropin-Releasing Hormone;Journal f�r Praktische Chemie/Chemiker-Zeitung;1994
5. Chapter 30. Peptide Stability in Drug Development: in vitro Peptide Degradation in Plasma and Serum;Annual Reports in Medicinal Chemistry;1993
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