Effect of simvastatin (MK-733) on the regulation of cholesterol synthesis in Hep G2 cells

Author:

Yasufumi Nagata,Yusuke Hidaka,Fumiaki Ishida,Toshio Kamei

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference40 articles.

1. 3-Hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors. 4. Side chain ester derivatives of mevinolin;Hoffman;J Med Chem,1986

2. Mevinolin: A highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent;Alberts,1980

3. Preventive effect of MK-733 (Simvastatin), an inhibitor of HMG-CoA reductase, on hypercholesterolemia and atherosclerosis induced by cholesterol feeding in rabbits;Kobayashi;Jpn J Pharmacol,1989

4. Inhibitory effects of MK-733 on cholesterol synthesis in primary cultured rat hepatocytes;Ishida;Cell Struct Fund,1987

5. Effects of synvinolin (MK-733) on plasma lipids in familial hypercholesterolaemia;Mol;Lancet,1986

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