Enantioselective metabolism of encainide by rat liver microsomes

Author:

Jajoo Hemant K.,Prakash Chandra,Mayol Robert F.,Blair Ian A.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference12 articles.

1. Encainide: A review of the pharmacological properties and therapeutic efficacy;Brogden;Drugs,1987

2. Influence of genetic polymorphism on the metabolism and disposition of encainide in man;Wang;J Pharmacol Exp Ther,1984

3. Structural characterization of urinary metabolites of the antiarrhythmic drug encainide in human subjects;Jajoo;Drug Metab Dispos,1990

4. Antiarrhythmic activity, electrocardio-graphic effects and pharmacokinetics of the encainide metabolites O-desmethyl encainide and 3-methoxy-O-desmethyl encainide in man;Barbey;Circulation,1988

5. Possible contribution of encainide metabolites to the long term antiarrhythmic efficacy of encainide;Winkle;Am J Cardiol,1983

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